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Not All Dietary Fiber Is Created Equal


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News image: Not all dietary fiber is created equalBy Cara Murez HealthDay Reporter

Thursday, April 26, 2022 (Health Day News)

Dietary Fiber Receives a lot of praise for helping people to feel full and reduce the risk of certain types of diseases.

Yet many types of diets Fiber Exist – and they don’t all do the same thing, according to a small new study.

Michael Snyder, a professor of genetics at the Stanford University School of Medicine and co-author of the chair study, said, “When you actually get into it, the fibers are incredibly different. It’s very, very different.” “It’s like saying that all animals are the same.”

His team focused on two popular fibers Supplementary part To see how they are affected Cholesterol And blood Sugar. Most people get very little fiber in their dietAnd Supplementary part This could potentially close the gap, the researchers said in a background note.

Arabinoxylan is a commonly found fiber Supplementary part Such as Metamucil and psyllium husk. Inulin is found naturally in fruits and vegetables such as bananas and asparagus.

“It simply came to our notice then CholesterolSaid Snyder.

Another fiber, inulin, did not work Cholesterol lowering In most participants, however, it causes inflammation and some high levels of a marker spike Liver Loss

The blood did not decrease Sugar.

“People still react differently,” Snyder said. “There are some people who did not respond to arbinoxylan, but ironically, they reduced it. Cholesterol Including inulin. There is at least one participant who did it. “

The study included 18 healthy individuals who volunteered for three sessions, each three weeks long. For one session, participants took 10 grams of chicory inulin or arabinoxylan daily for one week, then 20 grams per day for one week and 30 grams per day for one week.

The volunteers took six to eight weeks off when they ate what they normally ate. When they return, they follow the same protocol but for other supplements.

During the third session, they took a supplement containing five types of fiber that included inulin and arabinoxylan.

Participants log their food and provide their blood, urine and samples Stool.

Researchers have measured the levels of intestinal bacteria, genes, proteins and their activity Lipids. The aim of the effort was to get a readout of all the metabolic and microbiological effects of fiber.

The research team found the most variation in measurements related to intestinal bacteria. Some of these bacteria increase when more arabinoxylan is consumed and some decrease, and increase regardless of how many arabinoxylan is consumed. All tested Supplementary part Transferred a participant’s composition Microbiome (Collection of germs living in the body), according to research.

There were drops in many participants who took high doses of arabinoxylan LDL cholesterol, “Bad” cholesterol. Those who took mixed supplements also had drops, but not so much.

During the study, researchers further found that arabinoxylan removes cholesterol from the body not by binding, as previously suspected, but by converting it to bile acids, Snyder said.

“We’ve come up with a whole new process on how cholesterol is probably reduced and it also involves your microbiome,” Snyder said.

When arbinoxylan is reduced LDL cholesterol For most participants, some experience a small reduction. Researchers believe that there may be a link between eating protein.




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In insulin studies, researchers have found a spike of inflammation in most people and at the highest levels Liver Damage identifier between three persons. Yet, in one person, high levels of insulin are reduced Inflammation.

One way of conducting the main study is that participants respond differently, Snyder said.

“You shouldn’t just assume, ‘I’m going to take it, it’s going to work.’ I think you should take it and say, ‘Now, has it worked on me?’ “Snyder said.

The team is studying arbinoxylan and inulin, as well as two additional types of fiber.

“It’s here now, but there’s no question we should be able to make predictions about it,” Snyder said. “We’re not there yet.”

The results were published on 28 April Cell host and microbe.

Directed by Dr. Natalie Bello High blood pressure Research at Smidt Heart The Cedars-Sinai Institute in Los Angeles.

Some of the people who had the opposite reaction to the study “hammered the need for personalized treatment strategies,” said Bello, who was not involved in the study.

“Our understanding of the interaction between food components and the microbiome is in our infancy, so examining dietary patterns and fiber supplements will be helpful in future work,” Bello said.

Previous data have shown the benefits associated with high dietary fiber intake and low Blood pressureBello said, but a high fiber Food Not for everyone.

“Healthy Food Including regular ExerciseEnough Sleep And Blood pressureBlood Sugar And the mainstay of improving cholesterol control Heart Health, “said Bello Fat Call Lipids Dash included, Vegetarian And the Mediterranean, he added.

More info

US Centers for Disease Control and Resistance There are more High cholesterol prevention.

Sources: Michael Snyder, PhD, Professor and Chair, Genetics, Stanford University School of Medicine, Stanford, California; Natalie Ann Bello, MD, MPH, Director, High blood pressure Research, Smith Heart Institute, Cedars-Sinai, Los Angeles; Cell host and microbeApril 28, 2022

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